İstanbul Galata Üniversitesi Kurumsal Akademik Arşivi
DSpace@Galata, İstanbul Galata Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Predictive Value of Complete Blood Count Parameters for Alzheimer's Disease in Relation to Periodontal Status
(Bentham Science, 2025) Karaduran, Kübra; Aydoğdu, Ahmet; Gelisin. Özlem; Günpınar, Sadiye
Given the role of inflammation in the development of both Alzheimer's disease (AD) and periodontal disease, it is plausible that periodontal disease may influence the progression of AD. Complete blood count (CBC) parameters may also serve as predictive indicators for this condition. This study investigated the predictive value of CBC parameters on the progression of AD in patients with periodontal disease.
Alzformer: Video-Based Space-Time Attention Model For Early Diagnosis Of Alzheimer’s Disease
(Pergamon-Elsevier Science, 2025) Akan, Taymaz; Akan, Sara; Alp, Sait; Ledbetter, Christina Raye; Bhuiyan, Mohammad Alfrad Nobel
Early and accurate Alzheimer’s disease (AD) diagnosis is critical for effective intervention, but it is still challenging due to neurodegeneration’s slow and complex progression. Recent studies in brain imaging analysis have highlighted the crucial roles of deep learning techniques in computer-assisted interventions for diagnosing brain diseases. In this study, we propose AlzFormer, a novel deep learning framework based on a space–time attention mechanism, for multiclass classification of AD, MCI, and CN individuals using structural MRI scans. Unlike conventional deep learning models, we used spatiotemporal self-attention to model inter-slice continuity by treating T1-weighted MRI volumes as sequential inputs, where slices correspond to video frames. Our model was fine-tuned and evaluated using 1.5 T MRI scans from the ADNI dataset. To ensure the anatomical consistency of all the MRI data, All MRI volumes were pre-processed with skull stripping and spatial normalization to MNI space. AlzFormer achieved an overall accuracy of 94 % on the test set, with balanced class-wise F1-scores (AD: 0.94, MCI: 0.99, CN: 0.98) and a macro-average AUC of 0.98. We also utilized attention map analysis to identify clinically significant patterns, particularly emphasizing subcortical structures and medial temporal regions implicated in AD. These findings demonstrate the potential of transformer-based architectures for robust and interpretable classification of brain disorders using structural MRI.
The Mediating Role of Psychological Empowerment and Trust in Leader on the Effect of Inclusive Leadership on Innovative Work Behavior: A Field Study in the Textile Industry in Turkiye
(Sage Publishing, 2025) Amirli, Hamran; Fettahlioğlu, Ömer Okan; Gül, Necmettin; Tatli, Hasan Sadik
The research is conducted with employees in the textile sector operating in Kahramanmarasx/T€urkiye. The study aims to examine the effect of inclusive leadership on employees’ innovative work behavior, as well as the mediating roles of trust in leader and psychological empowerment in this interaction. This cross-sectional study collected data from 275 employees in the textile industry of Kahramanmarasx/T€urkiye. The data were analyzed by the structural equation modeling (SEM) method using SmartPLS 4 software. The results of the analysis revealed that inclusive leadership has a direct positive effect on IWB. In addition, it was determined that inclusive leadership increases psychological empowerment and trust in leader. While psychological empowerment was found to have a significant mediating role in the relationship between inclusive leadership and innovative work behavior, the mediating role of trust in leader was not supported. The findings suggest that focusing on psychological empowerment in inclusive leadership practices is effective in increasing IWB. The limited effect of trust in leader on innovative work behavior indicates the complexity of leadership and employee interactions. Theoretical and practical implications and recommendations are presented at the end of the study.
Evaluation of Gastrointestinal Life Quality and Food Consumption and Choices in Recovered Covid-19 Patients
(2023) Baş, Dilşat; Talak, Şengül Sangu; Ozman, Nur Ecem Baydı; Kitay, Deniz Nadide; Çatırtan, Hazal; Binöz, Ayşe Sena; Öngen, Nilay; Onganer, Efe; Baş, Murat
Background/Objectives: This study explores how gastrointestinal symptoms affect patients’ nutrition, food choices, consumption, and gastrointestinal quality of life index (GIQLI) scores after recovering from COVID-19. Subjects/Methods: A questionnaire-based cross-sectional study was conducted among patients aged 18 and older who recovered from COVID-19 between 15th May 2020 and 15th June 2020. The researchers sent 594 patients a questionnaire via e-mail, which included demographical information and questions related to supplement use, food choices, and a survey for GIQLI. Seventy-six patients who responded and consented to take the questionnaire were included in the final analysis. Results: Weight loss post-COVID was significant for both male and female genders (-5.1± 4.0 vs. -1.5 ± 2.4; p-value:0.001). The length of hospitalization, the loss of appetite, and the loss of smell were significantly higher in male participants (P<0,05). The mean GIQLI score was significantly higher in males compared to females (102.2± 14.6 vs. 89.5 ± 23.2; p=0.003). Gender and regular probiotic use before and after hospitalization were correlated with the total GIQLI score (R = 0.646; R2 = 0.417) Conclusion: COVID-19 affects the Gastrointestinal system (GIS) and appetite. Therefore, healthy nutrition, well adapted to the body’s needs and the current level of physical activity, becomes particularly important during and post-COVID. In addition, the treatment of gut dysbiosis involving an adequate intake of pre and probiotics could be a beneficial instrument for modulating the immune system in COVID-19 patients and prophylactically pre-infection. Therefore, we recommend integrating probiotic use into current COVID-19 nutritional guidelines.
Linking Human Capital to Innovation Capability: A Dynamic Capabilities Perspective
(2024) Tatlı, Hasan Sadık
The research examines the mediating role of dynamic capabilities in the effect of human capital on innovation capability. The research was conducted with white-collar employees in a logistics company based in Istanbul. A simple random sampling technique was used to determine the sample. The research sample is 238 employees working in the same company for at least three years. Mediation models were used to analyse the data. The data analysis determined that employee capital significantly increases the company's dynamic and innovation capabilities. In addition, the company's dynamic capabilities mediate in forming the innovation capability of employee capital. The hypotheses created within the scope of the research were supported. Human capital companies' dynamic capabilities effectively form the company's dynamic capabilities and subsequently obtain innovation capabilities. The research contributes to the literature by associating employee capital, innovation capability, and dynamic capabilities in the logistics sector.
