İstanbul Galata Üniversitesi Kurumsal Akademik Arşivi
DSpace@Galata, İstanbul Galata Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Mindful eating as a supportive intervention for breast cancer survivors: a pilot randomized controlled trial
(Springer, 2026) Baş, Dilşat; Ağır, Gizem; Sönmez, Özlem; Önes, Ece
Background Breast cancer (BC) survivors often face weight management and disordered eating challenges that may impair quality of life. This pilot randomized controlled trial evaluated the effects of a six-session mindful eating intervention on eating behaviors and body composition in BC survivors. Methods Breast cancer survivors were enrolled in a pilot randomized clinical trial and randomly assigned to mindful eating intervention plus treatment-as-usual (TAU + MEI, n = 13) or treatment-as-usual alone (TAU, n = 15). Intuitive and mindful eating were assessed using the Intuitive Eating Scale-2 (IES-2) and the Mindful Eating Questionnaire-30 (MEQ-30). Anthropometric measures were assessed monthly over six months. Longitudinal changes were analyzed using repeated-measures ANOVA and generalized estimating equations (GEE). Results Reliance on hunger and satiety cues increased significantly over time in both groups (TAU: p = 0.004; TAU + MEI: p = 0.007). Significant improvements were observed in selected mindful eating dimensions, including disinhibition, emo-tional eating, eating control, and eating with attention and intention (all p < 0.05). MEQ-30 total scores increased significantly in both groups (TAU: p < 0.001; TAU + MEI: p = 0.010). Waist circum-ference decreased significantly in the TAU group (p = 0.002), while hip circumference decreased in the TAU + MEI group (p = 0.009). GEE analysis showed that participation in the TAU + MEI group was independently associated with lower BMI over time (p = 0.013), whereas HR(+)/HER2(-) sub-type and chronic disease were associated with higher BMI (all p < 0.05). Conclusions Both TAU and TAU + MEI were associated with improvements in selected eating-behavior and anthropometric outcomes over time, including indicators of central adiposity, with no clear overall superiority of TAU + MEI across the outcomes assessed. These exploratory findings support further investigation of incorporating mindful eating into standard nutritional care for breast cancer survivors.
Intelligent Periodontics: Integrating Artificial Intelligence and Nanotechnology in Next-Generation Prosthetic Dentistry
(Tehran University of Medical Sciences, 2026) Haghverdi, Fatemeh; Salehi, Nushin; Farokhnia, Hasti; Rouzbahani, Faezeh Gandomi; Chahardoli, Mohammad Reza; Madani, Maryam; Armand, Nafiseh
This review explores how combining artificial intelligence and nanotechnology can reshape periodontics and prosthetic dentistry by enabling more precise, predictive, and personalized care. It first outlines the conceptual foundations of intelligent periodontics, emphasizing data driven decision making, the shift from conventional to digital workflows, and the integration of AI into routine diagnostic and therapeutic processes. The paper then examines current AI applications in periodontal diagnosis, disease progression prediction, and prosthodontic workflows, highlighting improvements in imaging analysis, treatment planning, and prosthesis design. In parallel, it reviews nanotechnology based strategies for periodontal regeneration, implant surface modification, antimicrobial coatings, and targeted drug delivery, focusing on their contribution to enhanced tissue integration and long term clinical performance. The convergence section discusses AI assisted design and optimization of nanomaterials, smart and responsive nano systems, and data driven development of next generation implants and prostheses. Clinical translation challenges including nanotoxicity, data privacy, algorithmic bias, regulatory gaps, cost, and training needs are critically analyzed, alongside future trends such as nanorobotics, AI enabled precision prosthodontics, and IoT based smart oral devices. Overall, the review provides a structured framework for responsibly integrating AI and nanotechnology into modern periodontal and prosthetic practice, aiming to support more effective, safe, and patient centered dental care. © 2026 Tehran University of Medical Sciences. All rights reserved.
Influence of Different Surface Modifications on the Reverse Torque Values of Abutment Screws: An In Vitro Study
(2026) Dede, Merve; Özyılmaz, Özgün Yusuf; Doğanay Özyılmaz, Özge; Hancı Abay, Gamze
Evidence regarding tantalum nitride (TaN)-coated gold abutment screws is lacking, and studies on diamond-like carbon (DLC)-coated and anaerobic adhesive-coated abutment screws remain limited. This study evaluated the reverse torque values (RTVs) of abutment screws with different surface modifications. Sixty abutment screws from the same implant system were divided into five groups (n = 12): gold, TaN-coated gold, titanium, DLC-coated titanium, and anaerobic adhesive-coated titanium. Abutments were tightened according to the manufacturer’s recommended torque. Specimens were then subjected to cyclic loading (50 N, 1 Hz, 480,000 cycles) in a dual-axis chewing simulator, after which RTVs were evaluated. ANOVA showed a significant difference only for the uncoated gold screw group (p < 0.05). The lowest RTVs were observed in the gold screws. Although the differences among the modified screw groups were not statistically significant, surface-treated screws demonstrated higher and more stable RTVs than their uncoated counterparts. TaN-, DLC-, and anaerobic adhesive-treated screws exhibited higher RTVs following cyclic loading, suggesting that these surface modifications may enhance screw stability and reduce the risk of abutment screw loosening.
Efficacy of transabdominal magnetic field therapy on constipation severity in chronic functional constipation: A randomized controlled trial
(Professional Medical Publications, 2026) Elverişli, Gizem Boztaş; Özkaraoğlu, Dilanur Kutlu; İnce, Büşra; Ataç, Amine; Atılgan, Esra
Objectives: To evaluate transabdominal magnetic field therapy (MFT) for constipation severity and related outcomes in adults with chronic functional constipation. Methodology: This multicenter, three-arm randomized controlled trial was conducted at Istanbul Medipol University and Istanbul Gedik University, Türkiye, from February 2019 to April 2026. Adults meeting Rome III criteria were randomized to MFT, sham, or standard care (SC) (n=75); 60 completers formed the per-protocol analysis (20/group). MFT was administered at 25-Hz and 30-Gauss for 30 minutes, twice weekly for eight weeks. Sham replicated the procedure without active stimulation; SC received standardized constipation management education. The primary outcome was the Constipation Severity Instrument (CSI) total score. Secondary outcomes assessed bowel habits, defecation time, stool form, and constipation-related quality of life (PAC-QOL). Results: MFT reduced CSI more than SC (mean difference in change [MD], -20.55; 95% CI, -24.97 to -16.13) and sham (MD, -14.40; 95% CI, -18.82 to -9.98; both p<0.001). MFT also improved complete spontaneous bowel movements versus SC (ratio of rate ratios [RRR], 1.57; 95% CI, 1.20-2.05) and sham (RRR, 2.39; 95% CI, 1.87-3.07), and reduced PAC-QOL versus SC (MD, -21.25; 95% CI, -24.09 to -18.41) and sham (MD, -11.60; 95% CI, -14.44 to -8.76; all p≤0.001). No adverse events were observed or reported among completers. Conclusions: Transabdominal MFT was associated with greater short-term improvements in constipation severity, bowel function, and constipation-related quality of life than sham treatment and standard care. Future studies should establish optimal stimulation parameters and evaluate long-term effectiveness and safety.
Acute responses to local tibialis anterior fatigue: Effects on dynamic balance and muscle mechanical properties
(Sage Publishing, 2026) İlez, Ali; Şahbaz, Yasemin; Batur, Nergiz
Background: Local muscle fatigue can influence the neural functional mechanisms and intrinsic mechanical properties of the muscle. Considering the importance of the tibialis anterior (TA) muscle during walking and upright standing positions, the primary aim of this study is to understand how induced local muscle fatigue affects both dynamic balance and changes in muscle mechanical properties. Methods: Thirty healthy participants (mean age: 21.83±1.41 years) were included in the study. Muscle mechanical properties of the dominant TA were assessed using MyotonPro, and dynamic balance was evaluated bilaterally with the Modified Star Excursion Balance Test (mSEBT) before and after the fatigue protocol. The fatigue protocol was applied bilaterally to ankle dorsiflexor muscle muscles and consisted of repeated 30-s isometric dorsiflexion contractions followed by 15-s rest intervals, continued until participants reported a Borg Rating of Perceived Exertion score of 7 or higher. Result: Following the fatigue protocol, a significant improvement was observed in left mSEBT and right mSEBT scores (p < 0.05), except in the anterior direction, where no significant change was detected. Regarding muscle mechanical properties, stiffness decreased, but this change was not statistically significant (p =0.06), whereas relaxation time and creep significantly increased (p < 0.05). Conclusion: Localized ankle dorsiflexor muscle fatigue acutely altered both dynamic balance and muscle mechanical properties. The apparent improvement in mSEBT scores likely reflects short-term neuromuscular compensation rather than genuine performance enhancement. Decreased stiffness and increased relaxation indicate transient adaptations in the muscle’s passive behavior.
