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Öğe The Mediating Role of Climate Change Mitigation Behaviors in the Effect of Environmental Values on Green Purchasing Behavior within the Framework of Sustainable Development(Walter de Gruyter GmbH, 2025) Yilmaz, GoncaGlobal environmental challenges, including the depletion of natural resources, pollution, and population growth, have significantly impacted modern lifestyles. The environmental and socioeconomic dimensions of this reality are represented by climate change, one of the major threats facing the planet. People's environmental values and the green behaviors they exhibit based on these values are crucial in mitigating significant environmental problems, such as climate change. In this context, raising environmental awareness and motivating individuals to contribute to sustainable development and the circular economy particularly environmental protection can serve as an effective starting point. In line with this idea, data were collected from 236 participants in Istanbul in 2024 using the convenience sampling method. The data collected through the survey technique in the study were analyzed using the SPSS program and PROCESS, a macro developed for SPSS. In addition, confirmatory factor analysis and path analysis were performed with the Python programming language, and fit index was also presented. The research findings reveal a significant relationship between environmental values and green purchasing behavior. The mediating role of climate change mitigation behavior was also found.Öğe Deep Learning in neuroimaging for neurodegenerative diseases: State-of-the art, Challenges, and Opportunities(Elsevier B.V., 2025) Akan, Taymaz; Alp, Sait; Ledbetter, Christina Raye; Tafti, Ahmad P.; Arevalo, Octavio; Bhuiyan, Mohammad Alfrad NobelNeuroimaging is commonly used to diagnose neurodegenerative diseases (NDDs), providing crucial insights into brain changes before clinical symptoms manifest. Deep learning (DL) for neuroimaging can improve early diagnosis and disease monitoring. Clinical implementation of DL faces challenges in accurately representing realworld data. Recent models, particularly those focused on diagnostic categorization, have achieved high accuracy, but their applicability to patients is limited. Conflicting inferences have been reported, with findings from small cohorts generalizing conclusions without considering inter-scanner, intra- and inter-site variations. A theoretically feasible method involves gathering a comprehensive dataset that encompasses all patient demographics, but this presents practical challenges including harmonization, data incompleteness, class imbalance, and substantial costs. Existing research has also mostly focused on common NDDs like Alzheimer's Disease (AD) and Parkinson's Disease (PD). This contribution expands the literature by looking at a wider range of NDDs, exploring the latest advancements in applying deep learning algorithms to neuroimaging analysis for the diagnosis and monitoring of NDDs, including AD, Frontotemporal Dementia (FTD), Lewy Body Dementia, PD, Huntington's Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis. We emphasize how these approaches are handling spatial/temporal information available in brain volume imaging data. We conclude by discussing the challenges associated with the use of voxel-based, patch-based, ROI-based, and slice-based approaches in brain volume imaging. These challenges are further compounded by issues such as inter-site and inter-scanner variability, class imbalances in medical datasets, and the scarcity of accurately annotated data, all of which impact the performance and generalizability of deep learning models.Öğe Adapting the metaverse perception scale for Iranian nursing students: translation and psychometric assessment(Springer, 2025) Aghabarary, Maryam; Yıldırım, Tuğba Öztürk; Norouzinia, RoohangizThe integration of metaverse technologies into healthcare education is expand ing globally. However, there is a lack of culturally validated instruments to assess students’ perceptions within the Iranian context. This study aimed to evaluate the psychometric properties of the Persian version of the Metaverse Perception Scale among Iranian nursing students. A cross-sectional psychometric study was con ducted with 436 nursing students. The translated scale underwent Exploratory Fac tor Analysis (EFA) and Confirmatory Factor Analysis (CFA). Internal consistency was assessed using Cronbach’s alpha. Convergent and discriminant validity were evaluated through Composite Reliability (CR), Average Variance Extracted (AVE), inter-construct correlations, √AVE, MSV and ASV. Factor analysis revealed a four factor structure—Education, Technology, Lifestyle, and Challenges—which ex plained 67.08% of the total variance. CFA results indicated that the refined 20-item version of the questionnaire had a good overall model fit (χ²/df=1.647; CFI=0.958; RMSEA=0.054). All CR values and AVE values were above 0.70 and 0.50, re spectively, supporting convergent validity. For all factors, √AVE values exceeded inter-construct correlations, and both MSV and ASV were lower than AVE, sup porting discriminant validity. The scale demonstrated strong internal consistency (Cronbach’s alpha=0.917−0.822). The Persian version of the Metaverse Perception Scale (P-MPS) is a valid and reliable scale for assessing nursing students’ percep tions of metaverse technologies in educational settings. This scale shows strong potential for application in both researcÖğe Smart Contracts, Blockchain, and Health Policies: Past, Present, and Future(Multidisciplinary Digital Publishing Institute (MDPI), 2025) Kurt, Kenan Kaan; Timurtaş, Meral; Ozaydin, Fatih; Türkeli, SerkanThe integration of blockchain technology into healthcare systems has emerged as a technical solution for enhancing data security, protecting privacy, and improving interoperability. Blockchain-based smart contracts offer reliability, transparency, and efficiency in healthcare services, making them a focal point of many studies. However, challenges such as scalability, regulatory compliance, and interoperability continue to limit their widespread adoption. This study conducts a comprehensive literature review to assess blockchain-driven health data management, focusing on the classification of blockchain-based smart contracts in health policy and the health protocols and standards applicable to blockchain-based smart contracts. This review includes 80 core studies published between 2019 and 2025, identified through searches in PubMed, Scopus, and Web of Science using the PRISMA method. Risk of bias and methodological quality were assessed using the Joanna Briggs Institute tool. The findings highlight the potential of blockchain-enabled smart contracts in health policy management, emphasizing their advantages, limitations, and implementation challenges. Additionally, the research underscores their transformative impact on digital health policies in ensuring data integrity, enhancing patient autonomy, and fostering a more resilient healthcare ecosystem. Recent advancements in quantum technologies are also considered as they present both novel opportunities and emerging threats to the future security and design of healthcare blockchain systems.Öğe Comparison of University Students' Awareness of Radiation Protection before and after Hospital Internship(The Korean Association for Radiation Protection, 2025) Colak, GülcihanThis study aims to compare the pre-and post-application results of university students' knowledge regarding radiation protection. Materials and Methods: The study was conducted on 116 students enrolled in the medical imaging and radiotherapy program. These students were administered a two-stage, 33-item radiation protection knowledge scale via Google Forms before and after the application course. The application results were analyzed as pre-test and post-test. Results and Discussion: A total of 116 students participated in the study. According to the study results, there was a difference in the students' awareness of the radiation protection sub-factor before and after the application. The primary reason for this is that observing the use of protective equipment during the application has increased their awareness. The importance of protective equipment for both worker health and patient safety has been understood. Conclusion: This study demonstrated the necessity of recording and monitoring radiation exposure during diagnosis and treatment procedures. The need to implement safety protocols to minimize the potential consequences of radiation hazards has also been recognized.Öğe From unmet childhood needs to parenting attitudes: breaking the cycle(Taylor and Francis, 2025)Objective: Rooted in Schema Therapy, this research posits that unmet physiological, social, and psychological needs during early life contribute to the development of enduring cognitive frameworks, termed early maladaptive schemas (EMS), which influence affect, behaviour, and cognition across the lifespan. Accordingly, the objective was to examine whether EMSs are systematically associated with specific parenting attitudes (PAs). Method: This correlational study employed a concurrent design. Participants included 246 volunteer parents of preschool-aged children residing in a cosmopolitan district of Istanbul. Data were collected online using validated measures of EMS and PA, along with additional items assessing potential confounding variables. Results: Correlational analyses revealed moderate positive associations between EMS and authoritarian parenting attitudes and moderate negative associations with democratic parenting attitudes. Hierarchical regression analyses showed that EMS accounted for over 20% of the variance in parenting attitudes, with socioeconomic status and education emerging as significant moderators. Discussion: EMSs significantly predict parenting attitudes, increasing authoritarian attitudes, and reducing democratic ones. Early identification of EMS, combined with schema-focused interventions and evidence-based parent education programs may help disrupt maladaptive parenting cycles and promote healthier parent–child dynamics.Öğe The Effect of Osteopathic Manipulative Treatment Adjunct on Stabilization Splint Treatment in Temporomandibular Joint Anterior Disc Displacement with Reduction Disorder: A Quantitative Analysis, Pilot Study(MDPI, 2025) Aklar, Ayca; Bal, Burcu; Tasdelen, Neslihan; Ertas, GokhanObjective: This study aimed to quantitatively assess the efficacy of osteopathic manipulative treatment (OMT) as an adjunct to stabilization splint treatment for temporomandibular joint anterior disc displacement with reduction (ADDwR) disorder. Method: Thirty-eight joints were evaluated in this study. OMT, in addition to splint treatment, was administered to the study group, and the control group only received splint treatment. Before and after the treatments, the quality of life, the pain levels of distinct body regions, and the sleep quality were evaluated, while mandibular movements were assessed and condyle–disc position differences measured on magnetic resonance images. Results: In all the life qualities, except social functionality, increases after treatment were present for both control and study groups, but the increase was significant in bodily pain for the control group (p = 0.034) while increases were significant in physical functionality (p = 0.018), general health perception (p = 0.027), and reported health transition (p = 0.019) for the study group. Significant pain reduction in all body regions was seen in the study groups (p = 0.007–0.033), but the decrease was only significant for the temporomandibular joint for the control group (p = 0.011). The sleep quality significantly improved for the study group (p = 0.018). Limited after-treatment improvements in the condyle–disc positions were determined for both the normal joints and joints with ADDwR in the study group. Conclusions: The application of OMT adjunct to splint treatment increases quality of life and sleep, reduces bodily pain, and improves condyle–disc positions over the MRIs of TMJ.Öğe Does inspiratory muscle training affect expiratory muscle thickness in respiratory intensive care patients? A pilot randomized controlled study(W B SAUNDERS CO-ELSEVIER INC, 2025) Benli, Reyhan Kaygusuz; Yilmaz, Baris; Yurdalan, S. UfukBackground: This randomized controlled trial aimed to compare abdominal muscle thickness between intensive care patients and healthy controls, and to evaluate the impact of IMT on expiratory muscle thickness using ultrasound. Methods: In this single-blind randomized controlled trial, 20 post-extubation intensive care patients were randomly assigned to either an a conventional physiotherapy (CP) group or IMT + CP group. Both interventions were applied for five days. An additional 10 healthy individuals served as controls for comparison. Abdominal muscle thicknesses-including external oblique (EOA), internal oblique (IOA), transversus abdominis (TRA), and rectus abdominis (RA)-were measured using ultrasound. Maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) were also recorded. Results: At baseline, healthy controls had significantly higher MIP, MIP% predicted, MEP, MEP% predicted, and RA muscle thickness compared to both patient groups (p < 0.05). Following intervention, both IMT and CP groups showed significant improvements in MIP (p < 0.05), but only the IMT group demonstrated significant increases in MEP, MEP% predicted, IOA, and RA muscle thickness (p < 0.05). The IMT group showed significantly greater improvements in MIP, MEP, IOA, and RA muscle thickness compared to the CP group (p < 0.05). Conclusion: Post-extubation IMT may improve not only inspiratory but also expiratory muscle strength and abdominal wall thickness. These findings suggest that IMT could support weaning processes in intensive care, although larger studies are needed.Öğe Skeletal muscle alterations in type 2 diabetes mellitus with and without dyslipidemia(BioMed Central Ltd, 2025) Satman, Ilhan; Dayican, Damla Korkmaz; Calikoglu, Fulya; Sahin, Humeyra Rekali; Perone, Francesco; Akinci, BuketBackground Diabetic dyslipidemia, a common comorbidity in people with type 2 diabetes, has been reported to be associated with adverse metabolic outcomes. Skeletal muscle is a key organ impacted by metabolic disorders; however, the specific effects of diabetic dyslipidemia on skeletal muscle mass, strength, and performance remain unclear. The aim of this study was to assess the skeletal muscle alterations of people with type 2 diabetes with and without dyslipidemia. Methods This retrospective study included 144 participants (mean age 51.3 +/- 7.1 years; 103 female, 41 male) aged 40-65 years. Body composition was assessed using bioelectrical impedance analysis (BIA), muscle strength via dynamometer, and functional capacity with the 6-minute walk test (6MWT). To minimize the confounding effect of longer diabetes duration in the diabetic dyslipidemia group, propensity score matching (PSM) was performed using a 1:1 nearest-neighbor method. All analyses were performed on matched groups. ROC analysis was conducted for variables showing significant differences. Results After PSM, people with diabetic dyslipidemia showed significantly lower skeletal muscle mass and skeletal muscle index (SMI), higher body fat percentage, and reduced 6MWD compared to those with diabetes alone (p < 0.05). In women with diabetic dyslipidemia, handgrip strength was significantly lower. ROC analysis revealed moderate predictive value for skeletal muscle mass (AUC = 0.682), SMI (AUC = 0.654), and 6MWD (AUC = 0.628). Conclusion This study demonstrated that people with diabetic dyslipidemia had lower skeletal muscle mass, SMI, and decreased physical performance compared to people with diabetes alone, even after matching for diabetes duration. These findings demonstrate early sarcopenic and dynapenic changes and highlight the need to consider skeletal muscle health and lipid abnormalities together in diabetes management.Öğe Volumetric Three-Dimensional Evaluation of the Pharyngeal Airway After Orthognathic Surgery in Patients with Skeletal Class III Malocclusion(Multidisciplinary Digital Publishing Institute (MDPI), 2025) Oz, Aslihan Zeynep; El, Hakan; Palomo, Juan MartinBackground: Orthognathic surgery significantly alters the dimensions of the pharyngeal airway. This study's objective was to assess alterations in the pharyngeal airway volume via cone-beam computed tomography (CBCT) after orthognathic surgery in patients with skeletal Class III malocclusion. Methods: This retrospective study analyzed CBCT images from 23 patients with skeletal Class III malocclusion (13 females, 10 males), who were categorized into two groups based on the surgical approach: double-jaw and single-jaw surgery. The double-jaw group included 13 patients who underwent bilateral sagittal split osteotomy (BSSO) and Le Fort I osteotomy, whereas the single-jaw group included of 10 patients who had underwent BSSO only. CBCT images were evaluated both before surgery and at a minimum of three months after surgery. The oropharyngeal volume (OP), nasopharyngeal volume (NP), total airway volume, posterior airway space (PAS), and the most constricted area at the base of the tongue (minAx) were measured. Statistical analyses were performed using either paired t-tests or Wilcoxon signed-rank tests depending on data normality, with a significance level set at p < 0.01. Results: In the double-jaw group, a significant volumetric increase was observed in the nasopharynx (5316 +/- 1948 mm(3) to 6064 +/- 1899 mm(3); p = 0.010) and oropharyngeal volume decreased from 17,097 +/- 5675 mm(3) to 14,290 +/- 5835 mm(3); however, this reduction was not statistically significant (p = 0.017). In contrast, the single-jaw group showed a significant reduction in oropharyngeal volume from 15,620 +/- 5040 mm(3) to 12,444 +/- 4701 mm(3) (p = 0.010), with no significant change in nasopharyngeal volume (p = 0.551). Total airway volume significantly decreased only in the single-jaw group (from 20,452 +/- 7754 mm(3) to 16,846 +/- 6529 mm(3), p = 0.010). Additionally, both groups exhibited marked decreases in PAS and minimum axial area values (all p < 0.01). Conclusions: Orthognathic surgery led to a significant volumetric increase in the nasopharynx in the double-jaw group, whereas the oropharynx volume significantly decreased only in the single-jaw group. Additionally, both surgical approaches resulted in a marked reduction in PAS and minimum axial area values, highlighting a notable impact on posterior airway dimensions.Öğe Cross-Cultural Adaptation and Validation of the Dance Functional Outcome Survey for Turkish Dancers (DFOS-TR)(CIENCE & MEDICINE INC, 2025) Tekin, Demet; Agopyan, Ani; Bronner, ShawIn dance, injuries are significant factors that can bring an active dance career to an end. A patient-reported outcomes questionnaire with established validity and reliability is useful for determining and evaluating the functional status of dancers before or after injuries. However, no valid and reliable survey is available in Turkish to assess dancers' functionality levels. The objective of this study was to translate, culturally adapt, and validate the characteristics of the Turkish version of the Dance Functional Outcome Survey (DFOS-TR) in adult dancers. METHODS: The DFOS-TR underwent forward translation, reconciliation, backward translation, and thorough review by an expert committee to ensure optimal alignment with the original English DFOS. A sample of 113 dancers (55 injured and 58 healthy) voluntarily participated in the research. Construct validity was assessed by comparing DFOS-TR to SF-36 using Pearson correlations; exploratory factor analysis and internal consistency were conducted; and sensitivity was evaluated through the generation of receiver operating characteristic curves and calculation of the area under the curve (AUC). Test-retest reliability was assessed by examining 26 dancers over a 15-day period, employing intraclass correlation (ICC). Various methods were employed, including ICC, standard error of measurement (SEM), minimal detectable change at the 95% confidence interval (MDC95), and standardized response mean (SRM). DFOS-TR scores were compared using paired samples t-test and two-way repeated measures ANOVA (p<0.05). The scores of injured dancers were examined to identify any floor or ceiling effects. RESULTS: The DFOS-TR demonstrated very high test-retest reliability (ICC=0.84). Single-factor loading in exploratory factor analysis confirmed the scale's unidimensionality and high internal consistency (a=0.79), A positive moderate correlation was found between SF-36 physical component and DFOS-TR total score (r=0.44; p=0.046) and activities of daily living (ADL) subscore (r=0.58; p=0.006). Cut-off value of 85.5 for DFOS-TR total score yielded in 87.3% sensitivity and 36.2% specificity. The scale did not exhibit ceiling or floor effects among the injured dancers, indicating robust measurement properties. CONCLUSION: The DFOS-TR can be used as a reliable, internally consistent, and effective measurement tool for Turkish-speaking dancers in health as well as during and after lumbar or lower extremity injuries.Öğe Mental Health in a Digital World: How Problematic Cell Phone Use and Personality Predict Fear of Missing Out (FoMO) in Gen Z University Students from Türkiye and the U.S.(YERKURE TANITIM & YAYINCILIK HIZMETLERI A.S, 2025) Yüksel,Peri; Huiqiao, HouObjective: The authors sought to examine the association between Fear of Missing Out (FoMO), mental health, personality traits, and social media use among Turkish and U.S. university students, belonging to Generation Z (Gen Z), born between 1997 and 2012, a cohort deeply immersed in technology and social media from an early age. Methods: The present online survey study included 637 university students aged 18-25 (20.09% male, 78.65% female, 1.26% other) from T & uuml;rkiye (86.03%) and the US (14.97%). Participants completed 19 sociodemographic questions, a 17-item FoMO Scale, and a 44-item Personality Inventory. The study analyzed the relationship between FoMO, mental health, personality traits, and social media use across different platforms. Results: Findings revealed that frequent cell phone use and higher FoMO scores were significantly associated with problematic social media use. TikTok users reported higher FoMO compared to non-users. Additionally, there was a positive correlation between the number of social media platforms used and FoMO. Social media use driven by boredom and passive observation further increased FoMO. Associations between FoMO and personality traits highlighted the role of individual differences in social media behaviors. Conclusion: The study highlights the need for tailored interventions that address both social media usage patterns and personality traits to reduce the negative impact of FoMO on mental health. While Gen Z are digital natives, they need to become digital experts to navigate the mental health challenges exacerbated by curated content and the prevalence of FoMO on social media. Universities play a crucial role in raising awareness and supporting students in managing these psychological pressures by promoting balanced digital behaviors. A deeper understanding of the interplay between digital behaviors, personality traits, and cultural contexts can inform future interventions aimed at reducing FoMO and enhancing the well-being of young people in an increasingly interconnected world.Öğe Anatomical Relationship of the Mylohyoid Ridge, Lingual Concavity, and Mandibular Canal: A Retrospective CBCT Study(Multidisciplinary Digital Publishing Institute (MDPI), 2025) Girit, Melike Nur; Ansen, Gamze; Pence, Kadriye Betul; Yuzbasioglu, NeslihanBackground/Objective: This study aimed to determine the position of the mylohyoid ridge (MR) and lingual concavity (LC) in the mandible and their relationship with the mandibular canal (MC) and submandibular fossa, to provide anatomical guidance for surgical procedures in this region. Methods: A retrospective analysis was performed on cone beam computed tomography (CBCT) scans from 200 adult patients who had undergone imaging for dental treatment. On cross-sectional images at the level between the first and second molar roots, the following measurements were obtained: LC horizontal depth, LC height, LC depth, MR height, MR depth, and the distances from MR to MC (MR–MC) and LC to MC (LC–MC). Results: Mean values were: LC horizontal depth: 3.72 ± 0.90 mm, LC height: 11.74 ± 2.01 mm, LC depth: 12.54 ± 3.03 mm, MR height: 17.66 ± 2.60 mm, MR depth: 6.87 ± 2.38 mm, MR-MC: 8.30 ± 2.00 mm, and LC-MC: 3.72 ± 0.87 mm. All parameters were symmetrical between the right and left sides of the mandible, with no significant sex differences. The positions of the MR and LC were related to each other, and the position of the MC was related to the positions of the LC and MR. There was no correlation between the horizontal depth of the LC and the position of the MR, LC and MC. Conclusions: The vertical positions of the MR and LC are related to each other and MC. Therefore, it can be used as a landmark in implant surgery.Öğe Organizational and Individual Antecedents of Resistance to Change: Organizational Climate and Technology Readiness(Sciendo, 2025) Eyitmiş, Ahmet Melih; Zümrüt, Muhammet ZekiBackground and purpose: There is interest in barriers to change in organizations. This research discusses factors affecting resistance to change based on employees’ technological competencies. This research aims to determine the mediating role of technology readiness in the effect of organizational climate in health institutions on resistance to change. Methodology: Research data were collected from 389 employees working in the healthcare sector. SPSS Process 2.13 macro was used to analyze the model. Results: According to the analysis results, organizational climate positively affected technology readiness. Additionally, organizational climate reduced resistance to change. In addition, employees’ readiness for technology reduced resistance to change. Finally, the mediating role of technology readiness (motivating and blocking factors) in the effect of organizational climate on resistance to change was significant. Further, a positive organizational climate in healthcare institutions increased employees’ readiness for new technologies and significantly reduced employees’ resistance to change. Conclusion: Creating a positive organizational climate can be vital in successfully implementing change processes in the healthcare sector. At the end of the research, theoretical and practical suggestions were presented. The research contributes to the literature by addressing the antecedents of resistance to change from organizational and individual perspectives.Öğe Balance and biomechanics: exploring lower extremity biomechanics in Parkinson’s disease(Springer Science and Business Media Deutschland GmbH, 2025) Duzenli, Senanur; Gunduz, Merve Sevinc; Yilmaz, Aysen Elif; Erdal, Yuksel; Mustafaoğlu, RüstemBackground: Postural instability (PI) is a symptom seen in 16% of Parkinson Disease (PD) patients and has limited response to dopaminergic therapy. Understanding the factors contributing to PI, such as biomechanical changes, is important for the development of non-pharmacological treatment. Aims: To investigate the relationship between lower extremity biomechanics and balance parameters in PD patients. Methods: A total of 18 participants (n = 9 female) were enrolled in the study. Lower extremity biomechanics were evaluated using a combination of measurements, including femoral anteversion angle, Q angle, leg length, navicular drop test (NDT), gastrocnemius shortness, range of motion (ROM) assessments, and the Foot Posture Index (FPI). Balance was assessed through the Postural Stability Test, Fall Risk Index (FRI), and the Mini-BESTest. Results: A significant correlation was observed between FRI and femoral anteversion (r = 0.58, p = 0.011) as well as hip flexion ROM (r = 0.67, p = 0.002) and lateral malleoli curvature (r = 0.48, p = 0.04). Overall Stability Index (OSI) was significantly associated with NDT (r = 0.53, p = 0.024) and forefoot abduction/adduction (r = 0.67, p = 0.002). The Anteroposterior Stability Index (APSI) correlated with NDT (r = 0.47, p = 0.048), knee flexion ROM (r = 0.47, p = 0.045), and forefoot abduction/adduction (r = 0.65, p = 0.004). Moreover, Mini-BESTest scores were associated with hip abduction (r = 0.55, p = 0.017), ankle plantar flexion (r = 0.63, p = 0.005), and knee flexion ROM (r = 0.47, p = 0.048). Conclusions: This study demonstrated that lower extremity biomechanical features, including alignment and joint mobility, are significantly linked to balance and fall risk in individuals with PD. Incorporating biomechanical assessments into clinical evaluations may aid in developing individualized treatment strategies for balance disorders in PD.Öğe Effect of different factors on microleakage and fracture strength of CAD-CAM produced inlays(John Wiley and Sons Inc, 2025) Subaşı, Meryem Gülce; Pekkan, Gürel; Arslan Malkoç, MeralPurpose: To investigate the effects of occlusal finish line, material, cement, and aging type on the microleakage and fracture strength of inlay restorations in vitro. Materials and Methods: Mesio-occluso-distal (MOD) inlay cavities were prepared in all teeth with an occlusal finish line in the form of a butt joint (BJ) or hollow-ground chamfer (HC) in one wall (buccal) (n = 80 each). Inlay restorations were designed using a computer-aided design and computer-aided manufacturing (CAD-CAM) device and milled from blocks (lithium disilicate ceramic [IPS e.max CAD] [LD] and resin nanoceramic [Lava Ultimate] [RN] [n = 40 each]). Inlay restorations were cemented to each tooth with dual-cure resin cement (RelyX Ultimate) (RU) or dual-cure self-adhesive resin cement (RelyX U200) (RU2) (n = 20 each). Specimens were divided into two groups (control [C] and thermomechanical aging [TM]) (n = 10 each). Microleakage and fracture strength tests were performed. The failure types were determined. Microleakage data (mm3) and fracture strength data (N) were analyzed by 4-way analysis of variance (ANOVA). Pairwise comparisons were made by Bonferroni testing. Fisher–Freeman–Halton testing was used to examine the relationship between categorical data. The correlation between microleakage and fracture strength was analyzed using Pearson's correlation analysis (p = 0.05). Results: Although the occlusal finish line, cement, and aging type affected the microleakage (p < 0.001), only the occlusal finish line type affected the fracture strength (p = 0.007). Relationships between the microleakage and fracture strength data were nonsignificant in all subgroups. Conclusions: For inlay restorations, an HC finish line and RU resin cement can be recommended. © 2025 by the American College of Prosthodontists.Öğe MRI-based alzheimer's disease classification using vision transformer and time-series transformer: a step-by-step guide(Elsevier B.V., 2025) Alp, Sait; Akan, Sara; Akan, TaymazThis study introduces a reproducible pipeline for classifying Alzheimer's Disease from structural brain MRI utilizing a joint transformer architecture that integrates Vision Transformer and Time-Series Transformer models. The proposed framework uses pre-trained ViT for feature extraction from 2D slices of MRI volumes, followed by sequential modeling with a transformer-based classifier to capture inter-slice dependencies. The method is evaluated on the ADNI dataset, involving both binary (AD vs. NC) and multiclass (AD, MCI, NC) classification tasks across axial, sagittal, and coronal planes.Öğe Predictors of stages of adoption of colorectal cancer screening among adults attending primary healthcare centers in Turkey(Springer, 2025) Dönmez, Elif; Ercan Toptaner, Nadire; Ata, Elvan E.; Dülger, Zeynep; Acar, OnurPurpose Although colorectal cancer (CRC) screening programs are known and recommended for reducing the mortality and morbidity rates from CRC, the adherence rates for the fecal occult blood test (FOBT) and colonoscopy are low among adult individuals. Moreover, CRC screening behaviors of primary health care patients remain largely unknown. The purpose of this study was to examine the predictors of stages of adoption for CRC screening in primary health care patients. Methods This cross-sectional study was carried out in primary health care centers with 498 adults between the ages of 50 and 70 years. The data were collected using the “Descriptive Form” and the “Instruments to Measure CRC Screening Benefits and Barriers.” Results The results indicate that colonoscopy was better known compared to FOBT, and information sources of screening tests were mostly relatives and family physicians. Most participants were at the precontemplation stage. Education level, employment status, income level, health status, having a patient diagnosed with CRC in the family, and having information about screening were related to the perception of benefits of having a FOBT and colonoscopy. On the other hand, adherence to colonoscopy, lack of knowledge about screening, and provider recommendation were related to perceived barriers. In addition, perceived benefits and barriers were predictive factors of earlier stages of adoption for FOBT and colonoscopy. Conclusion The results of the study demonstrate that primary care providers have crucial roles for increasing CRC screening in the community. Interventions to improve screening adherence rates should be tailored to individuals in particular stages of adoption for CRC screening.Öğe Comparison of conventional and modified sling suture techniques in free gingival graft operations-a randomized controlled clinical trial(BMC, 2025) Shakiliyeva, Sanubar; Şahin, Demet; Günpınar, Sadiye; Gursel, MihtikarBackground: The aim of this study was to investigate the effects of conventional suture (CS) and modified sling suture (MSS) techniques, applied in free gingival graft (FGG) surgery using gingival unit graft (GUT) and conventional graft (CG) techniques, on clinical parameters and graft dimensions. Methods: 52 individuals having Cairo Type 2 (RT2) and Type 3 (RT3) gingival recessions in mandibular anterior were divided into four groups as (a) GUT + MSS (n = 13), (b) GUT + CS (n = 13), (c) CG + MSS (n = 13) and (d) CG + CS (n = 13). Keratinized tissue width (KTW), relative gingival recession height (rGRH), and relative vestibule depth (rVD) measurements were recorded using a digital caliper and UNC 15 periodontal probe. Dimensional changes (Δ) of the graft surface area (GSA) was determined by ImageJ software. All measurements were done at baseline, 1st and 3rd months. Results: It was determined that the increase in KTW in the 1st and 3rd months in GUT + CS group was significantly higher than GUT + MSS group (p < 0.05). There was no statistically significant difference in Δ rVD and Δ rGRH values between the groups. When ΔGSA (mm2) values were compared between the groups, the decrease in the 1st and 3rd months in the CG + MSS group was found to be significantly higher than the GUT + MSS and GUT + CS groups (p < 0.05). Conclusion: Within the limits of this study, it can be concluded that keratinized tissue can be obtained successfully with both GUT or CG techniques in FGG surgery, on the other hand, regardless of the suture technique, GUT showed less graft shrinkage than CG.Öğe Investigation of the effect of ultraprocessed food consumption on asthma using pulmonary function tests(Sage Publishing, 2025) Özçalkap İçöz, Rümeysa; Alpaslan, Mehmet; Tural, SedaBackground: NOVA is a food classification system that classifies foods according to the scope and purpose of food processing, rather than nutrients. Asthma is usually characterized by chronic inflammation and respiratory symptoms such as wheezing, shortness of breath, chest tightness, cough, and variable expiratory airflow limitation. According to the NOVA food classification system, consumption of ultraprocessed foods (UPF) can affect asthma symptoms. Aim: In this study, the relationship between UPF consumption and pulmonary function test (PFT) results of asthma patients in adults aged 18 to 65 was investigated using biochemical parameters. Methods: This study was a cross-sectional study and, was conducted with 339 asthmatic participants diagnosed with asthma and receiving medical treatment. The participants' consumption of UPF was determined using a food frequency questionnaire. The evaluation of forced expiratory volume in one second (FEV1) (L/s) and forced vital capacity (FVC) (L/s) in the respiratory function tests was based on the percentage of the measured and expected values. Results: Although no significant relationship was found between % FEV1 expected value and UPF consumption (P > 0.05), it was concluded that % FVC expected and % FEV1/FVC values decreased with increasing UPF consumption (P < 0.05). Conclusion: It has been concluded that consumption of UPF worsens respiratory function and asthma prognosis. Therefore, replacing UPF and beverage products with healthier foods or food processing methods will play an important role in maintaining health.
