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Öğe Kings of the milky way: a homogeneous Gaia DR3 analysis of king open clusters and the galactic disc metallicity gradient(2026) Yontan, Talar; Bilir, Selçuk; Çakmak, Hikmet; Plevne, Olcay; Soyduğan, Esin; Taşdemir, Seval; Canbay, Remziye; Çınar, Deniz Cennet; Koç, Seliz; Karagöz, Hülya; Öztürk, Burçin Tanık; Akbaba, Furkan; Çalışkan, Özcan; Banks, TimothyThis study aims to establish an internally homogeneous set of structural, astrophysical, and kinematical parameters for King open clusters and to assess their role as tracers of the Galactic thin disc. We present a homogeneous structural, astrophysical, and kinematical analysis of 27 King open clusters using high-precision Gaia DR3 astrometry, photometry, and spectroscopy. Probable members are selected through astrometric criteria, from which mean trigonometric parallaxes and proper motions are derived, while structural parameters are obtained by fitting King surface-density profiles. Cluster reddenings, distances, metallicities, and ages are determined via a homogeneous Markov Chain Monte Carlo isochrone-fitting approach applied to Gaia colour-magnitude diagrams. The derived parameters span (Formula presented) -(Formula presented) mag, metallicities of (Formula presented) to (Formula presented) dex, ages from 17 to 6166 Myr, and heliocentric distances between 739 and 6272 pc. A comparison between astrometric and isochrone-based distances yields a median parallax difference of (Formula presented) as, indicating a good level of internal consistency between the photometric and astrometric distance scales within the adopted homogeneous framework. Using the resulting homogeneous parameter set, we then investigate the spatial distribution and orbital properties of the King clusters within the Galactic disc.The radial metallicity behaviour of the King clusters is also examined using three complementary Galactic distance definitions and compared with the metallicity-radius relations obtained independently from 164 spectroscopically analysed open clusters from the literature. The King-cluster gradients are close to (Formula presented) dex kpc−1 and are broadly consistent with those of the external reference sample, indicating that the homogeneously analysed King clusters follow the negative metallicity-radius trend traced by the broader thin-disc open-cluster population. Flatter gradients are found for young clusters, suggesting more homogeneous chemical enrichment at recent epochs. When dynamical constraints are applied to reduce the effects of radial migration and orbital blurring, the inferred gradient remains close to (Formula presented) dex kpc−1. The use of a strictly homogeneous analysis framework reduces inter-study systematics and provides a consistent astrophysical, chemical, kinematical, and orbital reference dataset for the King open-cluster sample. © 2026 COSPAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.Öğe Stress distribution in titanium and zirconia implants with full-arch prostheses: a finite element analysis(BMC, 2026) Saz, Bahattin; Özyılmaz, Özgün Yusuf; Özyılmaz, Özge DoğanayObjective The stress distribution and mechanical properties of materials used in dental implants are critically important for implant success and long-term stability. The aim of this study was to evaluate the stress distribution on implant, prosthetic system, and peri-implant tissues when titanium and zirconia implants are used with different framework materials using three-dimensional finite element analysis (FEA). Methods A three-dimensional edentulous maxilla model was reconstructed from computed tomography data, and twelve finite element models were subsequently developed based on this anatomy to represent different implant and framework configurations. Within the scope of the study, titanium and zirconia implants were modeled in combination with cantilevered and noncantilevered prosthesis types and Co-Cr, PEKK, and zirconium framework materials. An oblique static load of 200 N was applied at a 45° angle in the palato-buccal direction to the central fossa of the first molar on the models. The Von Mises and principal stress distributions in the implant, abutment, screw, framework, and peri-implant bone were examined. Results The highest Von Mises value was recorded in the cantilevered PEKK framework zirconia implant model (378.388 MPa). Compared with the Co-Cr and zirconium framework, the PEKK framework resulted in higher Von Mises stresses and greater prosthesis displacement. The presence of a cantilever increased stress levels in all framework materials, and stress concentrations were observed particularly in posterior abutments and peri-implant bone. Furthermore, stress values in trabecular bone were recorded above the physiological threshold level in the cantilevered PEKK framework models. Conclusions Although zirconia implants exhibited greater stress than titanium implants, they remained within safe limits. Rigid framework materials and cantilever-free designs provide more balanced biomechanical results.Öğe Nanotechnology in Endodontics and Prosthodontics: Current Advances and Future Perspectives(Tehran University of Medical Sciences, 2026) Amini, Parviz; Jafari, Elahe; Abbasi-Asl, Masoumeh; Haghverdi, Fatemeh; Motiei, MehrnazNanotechnology has emerged as a transformative force in modern dentistry, offering unprecedented advancements in both endodontics and prosthodontics through the manipulation of materials at the nanoscale. This review synthesizes current knowledge on nanotechnology applications in these fields, evaluating their impact on treatment outcomes, material performance, and patient care while critically addressing associated challenges and future research directions. In endodontics, nanoparticles have revolutionized root canal therapy by enhancing disinfection efficacy through superior penetration into dentinal tubules, significantly reducing reinfection risks and improving antimicrobial action. Nanomaterial-enhanced sealers and obturating materials exhibit improved mechanical properties, including increased strength, fracture resistance, and adhesion, thereby extending treatment durability. Furthermore, nanotechnology facilitates pulp tissue regeneration via targeted drug delivery systems and scaffolds that support stem cell differentiation and tissue revitalization. In prosthodontics, nanomaterials have dramatically improved the aesthetic and functional quality of dental restorations by closely mimicking the natural optical and structural properties of teeth while enhancing mechanical strength, wear resistance, and longevity. The integration of nanoparticles into prosthodontic materials has also resulted in superior surface hardness, modulus of elasticity, and reduced polymerization shrinkage, alongside antibacterial properties and controlled therapeutic agent delivery that promote oral health and patient comfort. Despite these promising advancements, significant challenges remain, including concerns regarding long-term biocompatibility, cytotoxicity, systemic toxicity, and environmental impact of nanomaterials. The lack of standardized regulatory frameworks and comprehensive clinical safety data further complicates their widespread clinical adoption. Future research must prioritize rigorous preclinical and clinical investigations to establish robust safety profiles, develop application-specific regulatory guidelines, and advance innovative technologies such as smart stimuli-responsive materials, personalized nanotherapies, and nanorobotic interventions. Sustained interdisciplinary collaboration among researchers, clinicians, and regulatory authorities will be essential to fully harness the transformative potential of nanotechnology in dentistry while ensuring patient safety and improved therapeutic outcomes. © 2026 Tehran University of Medical Sciences. All rights reserved.Öğe Effect of different laser modalities and treatment methods on the surface roughness and alterations of 3D printed resins and PEEK: An in vitro study(Elsevier, 2026) Karabağlı, İrem Çelikyürek; Çopuroğlu, Akanay; Kayahan, Zeynep Özkurt; Özyılmaz, Özgün YusufStatement of problem The effects of laser irradiation, airborne-particle abrasion, and electrolytic cleaning on the surface roughness of 3-dimensionally (3D) printed resin and PEEK healing abutments remain unclear. Purpose The purpose of this in vitro study was to examine surface changes after different treatment methods were applied to the surfaces of the different 3D printed resin and PEEK materials used as custom healing abutments. Material and methods Disk-shaped specimens (3×10 mm) were fabricated from three 3D printed resins (VarseoSmile TriniQ, Saremco Print Crowntec, C&B Ceramic Resin) and PEEK (CopraPeek) (N=240). Specimens were assigned to 5 surface treatment groups: erbium-doped yttrium aluminum garnet (Er:YAG), neodymium-doped yttrium aluminum garnet (Nd:YAG), diode laser, airborne-particle abrasion, and GalvoSurge (n=48). Surface roughness (Ra) was measured at baseline (T0) and after treatment (T1). Representative specimens were examined using scanning electron microscopy (SEM). Data were analyzed using nonparametric tests (α=.05). Results Airborne-particle abrasion and Er:YAG significantly increased surface roughness in all groups (P<.05). The highest roughness was observed in the Crowntec–airborne-particle abrasion group (0.89 ±0.09 µm), and the lowest in the TriniQ–GalvoSurge group (0.09 ±0.02 µm). GalvoSurge caused no significant change in TriniQ and PEEK but increased roughness in C&B and Crowntec. Nd:YAG showed no effect in TriniQ and C&B but increased roughness in Crowntec and PEEK, while diode laser affected only Crowntec (P<.05). SEM analysis confirmed treatment-dependent surface morphology changes. Conclusions Surface treatments altered resin and PEEK surface properties. Airborne-particle abrasion and Er:YAG laser treatments resulted in the greatest increases in surface roughness, while GalvoSurge and diode laser treatments generally caused minimal or nonsignificant changes.Öğe Zafirlukast Exacerbates Behavioral Seizure Activity and Blood–Brain Barrier Disruption Despite Modestly Reducing Neuronal Injury Markers in a PTZ‑Induced Early Epileptogenesis Mouse Model(Springer, 2026) Görgülü, Volkan; Tomruk, Cansın Şirin; Ergün, Pelin; Özdil, Berrin; Sancı, Ebru; Buhur, Aylin; Sözmen, Eser Y.; Köse, Timur; Yavaşoğlu, Nefise Ülkü Karabay; Yavaşoğlu, AltayEpilepsy is one of the most prevalent neurological disorders worldwide, and approximately 25% of patients remain refractory to pharmacological treatment. Blood–brain barrier (BBB) disruption and reactive gliosis are key mechanisms implicated in early epileptogenesis. This study investigated the effects of zafirlukast, a leukotriene receptor antagonist, on BBB permeability, reactive gliosis, and behavioral seizure activity in a pentylenetetrazol (PTZ)-induced early epileptogenesis model in C57BL/6 mice. Zafirlukast was administered twice daily at a dose of 10 mg/kg. Seizure activity was evaluated by behavioral observation in terms of seizure severity, latency, duration, and frequency. BBB permeability was assessed using the Evans Blue assay, and brain tissues were analyzed by biochemical and immunohistochemical methods. The PTZ + ZAFIR group exhibited more severe seizures, characterized by increased seizure frequency and duration, shorter latency, and a higher kindling rate (80% vs. 27%). BBB permeability was also increased, whereas MMP-9 levels remained, suggesting disruption may be linked to direct mechanical effects of recurrent seizures rather than inflammation. Clues suggest that zafirlukast may exert paradoxical effects on two prominent cell types involved in reactive gliosis. While increased GFAP and TGF-β1 expression may reflect enhanced astrocyte activation, changes in IL-1β and Iba1 expression suggest suppression of microglial activation. Notably, pro-inflammatory and oxidative stress markers remained unchanged despite the increase in seizure severity. The observed reduction in neurodegeneration may be attributable to the suppressive effects of zafirlukast on microglial activation and the subsequent reduction in pro-inflammatory cytokine release. These findings indicate a complex role for leukotriene signaling during early epileptogenesis. Further studies using different doses, vehicles, and experimental models are warranted to clarify the effects of zafirlukast on the mechanisms underlying early epileptogenesis. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2026.Öğe Asynchronous recovery of medial and lateral gastrocnemius mechanical properties and jump performance following localized plantar flexor fatigue(BMC, 2026) Şahbaz, Yasemin; İlez, Ali; Batur, NergizObjective: To investigate the acute and short-term (24 h) effects of localized plantar flexion fatigue on muscle mechanical properties, countermovement jump (CMJ) kinetics, and dynamic balance, focusing on recovery profiles of the gastrocnemius medialis (MG) and lateralis (LG). Design: Prospective, repeated-measures experimental study. Methods: Twenty-eight healthy volunteers (n = 28) performed a standardized unilateral isometric plantar flexion fatigue protocol until task failure (Borg CR-10 ≥ 8). Assessments were conducted at baseline, immediately post-fatigue, and 24 h post-fatigue (24 h). Outcomes included myotonometric properties (tone, stiffness, elasticity, relaxation time, and creep) of the MG and LG via MyotonPRO, CMJ kinetics via force plate, and dynamic balance via the Modified Star Excursion Balance Test (mSEBT). Results: Significant Time × Region interactions were found for stiffness (P = 0.038, ηp² = 0.276) and relaxation time (P = 0.024, ηp² = 0.171). Both muscle heads showed an acute decrease in stiffness (P < 0.001); however, LG stiffness recovered by 24 h (P = 0.330), while MG stiffness remained reduced (P < 0.05). Although CMJ height recovered at 24 h (P = 0.842), eccentric and braking phase durations remained prolonged (P < 0.001; ηp² = 0.357 and ηp² = 0.264), indicating altered neuromuscular strategies. For dynamic balance, a delayed impairment was observed in anterior reach distance, which declined only at 24 h compared to baseline (P = 0.021, ηp² = 0.133). Conclusion: Localized plantar flexion fatigue induces region-specific mechanical alterations and asynchronous recovery. Restoration of jump height at 24 h masks persistent deficits in eccentric phase durations and MG stiffness. These findings highlight a “neuromuscular vulnerability window” at 24 h post-fatigue, where delayed impairments in MG mechanics and anterior stability may increase potential susceptibility to injury despite apparent recovery. Practically, monitoring head-specific muscle mechanics, rather than global performance outcomes, is critical during this 24 h window to optimize training modification and guide objective return-to-play decisions. Trial registration: NCT07457398 (Registration date: February 25, 2026). © The Author(s) 2026.Öğe Classification of malignant/benign groups in lung cancer by machine learning and investigation of feature significance of parameters(Walter de Gruyter GmbH, 2026) Çalışkan, Gönül; Alataş, Emre; Köksal, Sevilay; Akyel, Reşit; Çavdar, İffet; Alçin, Göksel; Arslan, Esra; Çiftçi-Küsbeci, Tuba; Dereli, Elçin; Akgün, Elif; Tanyıldızı-Kökkülünk, Handan; Yiğit, ŞafakThis study aimed to apply machine learning (ML) models to enhance lung cancer (LC) classification, distinguishing malignant from benign tumors, using data from 73 patients. The dataset included PET/CT biomarkers and demographic factors, with SMOTE applied to address class imbalance. Three models were evaluated using 10-fold cross-validation to compare Random Forest (RF), Decision Tree (DT), Extra Trees Classifier (ETC), and XGBoost algorithms based on accuracy and AUC. ETC performed best in Model 1 (86% accuracy, AUC 0.95), RF in Model 2 (94% accuracy, AUC 0.97), and XGBoost in Model 3 (94% accuracy, AUC 0.98). XGBoost consistently outperformed others, particularly in Model 3, which included age and smoking. Feature importance analysis highlighted SUVmax as the most predictive variable, with smoking having a moderate influence and gender being minimal. Integrating clinical and lifestyle data with PET/CT parameters significantly improved LC classification. XGBoost emerged as the most effective model, demonstrating that comprehensive models enhance diagnostic accuracy beyond traditional metrics. © 2026 the author(s), published by De Gruyter, Berlin/Boston.Öğe Spatial characterization of the phoenixin receptor in the lacrimal and major salivary glands(2026) Gürler, Esra Bihter; Elmas, M.A.; Eyüpoğlu, I.P.; Arbak, S.; Çevik Aras, H.Objective: To identify and characterize the expression of phoenixin receptor GPR173 (G protein-coupled receptor 173) in the rat lacrimal and major salivary glands (parotid, submandibular, and sublingual). GPR173 is associated with hormonal regulation and autoimmunity; however, its expression in exocrine glands has yet to be characterized. Design: Under anesthesia, eight Sprague Dawley rats underwent bilateral dissection of the lacrimal and major salivary glands. GPR173 expression was assessed using Western blotting and immunofluorescence. Immunoreactivity was quantified using ImageJ software and compared using the Friedman test with DunnBonferroni post hoc analysis. Results: GPR173 protein expression was found in all examined exocrine glands. In the major salivary glands, GPR173 was detected in both acinar and ductal cells, while expression was confined to acinar cells in the lacrimal gland. The submandibular and parotid glands showed significantly higher immunoreactivity than the lacrimal gland (p < .01 and p < .05, respectively). Ductal epithelium showed stronger immunopositivity compared to acinar epithelium. GPR173 immunoreactivity was also observed in periductal stromal tissue in major salivary glands. Conclusion: GPR173 expression was observed in both acinar and ductal cells of all major salivary glands, while in the lacrimal gland, it was restricted to the acinar cells. This differential localization suggests tissue-specific relevance.Öğe Attachment and Relational Regulation in Esports Psychology: Understanding Performance in Digital Environments(Springer Nature, 2026) Balıkçı, ElifEsports has emerged as a rapidly professionalizing performance domain characterized by high cognitive demands, continuous social evaluation, and digitally mediated interaction. While research has largely focused on attentional, motor, and decision-making processes, the relational and regulatory dimensions of esports remain underexplored. Drawing on attachment theory, this chapter conceptualizes esports as a hybrid relational environment in which stress, evaluation, and mediated proximity simultaneously activate internal regulatory systems. It argues that digital communication channels may function as forms of secure base and safe haven, reorganizing attachment processes within technologically mediated contexts. Differences in attachment anxiety and avoidance are discussed in relation to performance stress, feedback sensitivity, team coordination, and long-term well-being. By moving beyond a purely cognitive account of esports performance, this chapter highlights the importance of relational regulation and psychosocial dynamics in sustaining high-level competitive play. Attachment theory is proposed as a holistic framework for understanding how players navigate threat, belonging, and exploration in the digital age. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2026.Öğe Assessment of Surface Roughness and Bacterial Adhesion of Occlusal Splints Fabricated with Different Layer Thicknesses, Polishing Techniques and Build Orientations(Multidisciplinary Digital Publishing Institute (MDPI), 2026) Dede, Merve; Saygılı, Sina; Topçuoğlu, NursenThis study evaluated the combined effects of build orientation, layer thickness, and polishing protocols on surface roughness and bacterial adhesion of occlusal splints. Ten disc-shaped specimens (Ø16 × 3 mm) were fabricated for each group using a digital light processing (DLP)-based 3D printer. Specimens were printed at two orientations (0° and 90°) and two layer thicknesses (50 and 100 µm) using a splint resin. Surface roughness was measured with a contact profilometer, and bacterial adhesion was measured by optical density (OD) readouts for Streptococcus mutans using a spectrophotometer. Surface morphology was examined by field-emission scanning electron microscopy (SEM). Statistical analyses were performed using jamovi. Because normality and/or homogeneity assumptions were not met, robust analysis of variance was applied. Polishing protocol significantly affected surface roughness (Ra) values. Unpolished specimens showed the highest Ra values, whereas mechanical polishing combined with centrifugation produced the lowest values. No significant main effects of polishing protocol, layer thickness or orientation were observed for bacterial adhesion. SEM findings supported the roughness results. Surface roughness was primarily influenced by polishing protocols and their interactions, whereas bacterial adhesion remained relatively stable. The weak Ra–OD correlation indicated that surface roughness alone was not a reliable predictor of bacterial adhesion.Öğe Comparison of W. Arnett’s cephalometric analysis measurements performed using artificial intelligence and manual measurements(Springer Science and Business Media Deutschland GmbH, 2026) Kula, Betül; Polat, Elif Nadide AkayObjectives: This study aimed to compare the linear and angular Arnett cephalometric measurements obtained from WebCeph Premium™ with those from manual cephalometric analysis and to assess the reliability of the automated measurements. Methods: Thirty-two pre-treatment lateral cephalograms of patients were randomly selected. Images were calibrated, 29 landmarks were manually traced, and 40 parameters were recorded by two orthodontists (6 angular, 34 linear). WebCeph Premium™ (version 2.0.0, AssembleCircle Corp., Gyeonggi-do, Republic of Korea) automatically identified landmarks and performed Arnett’s cephalometric analysis. After 15 days, orthodontists reassessed the radiographs. Reliability and repeatability were evaluated using the intraclass correlation coefficient (ICC), which exceeded 0.95, indicating excellent agreement. Normality was assessed using the Shapiro–Wilk test, and group comparisons were performed with paired t-tests. Results: For Researcher 1, initial ICC values ranged from 0.003 to 0.984 and final values from 0.617 to 0.996. For Researcher 2, initial ICC values ranged from 0.022 to 0.999 and final values from 0.601 to 0.999. Inter-observer ICC values ranged from 0.03 to 0.984, with most measurements showing high agreement. Manual tracing and WebCeph Premium™ showed high agreement, with ICC values ranging 0.913 and 0.995. Conclusions: WebCeph Premium™ demonstrates high concordance with manual Arnett analyses; however, further refinement of certain parameters is necessary to enhance AI precision. Clinical Relevance: The utilization of WebCeph Premium™ within clinical settings has the capacity to enhance the efficiency of cephalometric analysis for orthognathic cases by minimizing manual workload and inter-examiner variability. This can result in more consistent and efficient treatment planning. © The Author(s) 2026.Öğe From Norm Breach to Cascades: Judicial Responses to Suspect Interviewing Across Legal Cultures and the Cross-Norm Inhibition Effect(John Wiley and Sons, 2026) Kaya Cicerali, LütfiyeSuspect interviewing practices shape not only investigative outcomes but also the legitimacy of criminal justice systems. This article introduces the Cross-Norm Inhibition Effect (CNIE) as a theoretical framework explaining how tolerance of a single norm violation during interrogation can trigger cascading erosion of related procedural safeguards. Drawing on social-psychological research on norm inhibition and spillover, the article applies CNIE to suspect interviewing across adversarial, inquisitorial, hybrid, and human-rights–based legal systems. Using a conceptual-illustrative methodology, it analyzes recent high-court decisions across legal cultures to examine how judicial responses may contain, amplify, or reverse CNIE cascades, suggesting that CNIE functions as a conditional risk amplifier rather than a deterministic process. Weak safeguards and confession dominance may increase vulnerability to cascading distortions, whereas transparency, redundancy, and consistent judicial oversight may generate reinforcing compliance dynamics. Accordingly, this article contributes to debates on the implementation of the Méndez Principles and related rights-based interviewing reforms. © 2026 John Wiley & Sons Ltd.Öğe A rare form of schwannomatosis on the volar surface of the hand and wrist: A case report(Elsevier, 2024) Kıraç, Müge; Kara, Abbdullah Burak; Bulut, Halil İbrahim; Başdemir, Gülçin; Gümüş, Danyal; Özkan, KorhanBackground: Schwannomas, which are also known as neurilemomas, constitute the most common type of peripheral nerve tumors. These tumors can grow slowly and occur as painless swellings over the course of several years before their diagnosis. The aim of this report is to present a case of a very rare plexiform schwannoma originating from second digital nerve and multiple schwannomas from third and fourth digital nerves and palmar cutaneous branch of median nerve with emphasis given on differential diagnosis and treatment strategy. Case Presentation: A 15-year-old patient presented with soft tissue masses on the volar surface of the hand, initially diagnosed as benign nerve sheath tumors. Surgical excision was performed twice, preserving nerves and tendons. Recurrence occurred, and subsequent biopsy confirmed benign nerve sheath tumors. Microscopic examination revealed multinodular/plexiform schwannoma in the larger lesion and simple schwannomas in others, leading to a diagnosis of multiple schwannomatosis. All surgeries resulted in intact sensory and motor function. Conclusion: Surgical treatment can be curative and effectively employed for concomitant schwannoma tumors. Nevertheless, with careful planning and execution, surgery remains a promising option for patients with concomitant schwannomas. Further research and long-term follow-up studies are needed to fully understand the outcomes and refine the techniques used in these surgical treatments.Öğe Postoperative thirst in children: Experience of children's, parents and health professionals(2026) Şensoy, Özlem; Mert, Sabiha; Aydın, Ayfer; Şahin, CeylanThirst is one of the most distressing symptoms experienced by pediatric patients after surgery. This study aimed to explore and document the experiences of children, parents, and health professionals regarding postoperative thirst, providing insights to develop care strategies that address the emotional and psychological needs of pediatric patients. Design: A qualitative approach was employed to gather in-depth insights into the experiences of children, parents, and health professionals regarding postoperative thirst. Methods: Purposive sampling was employed in a Pediatric Surgery Unit, involving a total of 40 participants: ten children, sixteen parents, and fourteen health professionals. Semi-structured interviews were conducted with all participants, and the transcribed data were analyzed using qualitative content analysis. Findings: The content analysis revealed five themes: physical symptoms, feeling of discomfort, lack of knowledge, coping strategies, and suggestions. Conclusions: This qualitative study highlights the critical importance of addressing postoperative thirst in enhance the physical and emotional well-being of pediatric patients, emphasizing that thirst is not merely a physical symptom but a multidimensional experience that significantly affects children and their families. Implications to practice: This findings supports health professional should be educated on recognizing and managing postoperative thirst as a symptom in postoperative care. Integrating evidence-based thirst management strategies into postoperative care protocols can significantly improve patient outcomes, reduce anxiety, and promote recovery, ultimately advancing the quality of pediatric surgical care. © 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.Öğe The Impact of Social Media Based Advice on Health Behaviors in Digital Health Communication(Journal of Health Communication, 2026) Öngel, Volkan; Yurttaş, Özge Uluğ; Ateş, Gözde Bozkurt; Gümüşboğa, Yağmur; Mutlu, HaticeThe growing visibility of social media influencers has increased interest in their role in shaping health beliefs and behaviors. While prior research has largely focused on message characteristics or direct behavioral outcomes, less attention has been given to the conditions under which influencer-based health messages are interpreted and translated into action. This study conceptualizes influencer-based health communication not as a direct persuasive force, but as a conditional communication process. Drawing on Uses and Gratifications Theory and the Health Belief Model as interpretive frameworks, it examines how individuals engage with health-related influencer content, how such engagement relates to health perceptions, and how digital health literacy shapes message interpretation.Survey data from social media users were analyzed using Firth's penalized logistic regression to address the rarity of influencer-driven health behavior. Findings indicate that, despite high levels of exposure to influencer-based health content, the translation of such exposure into health-related action remains limited. Exposure to health content significantly increases the likelihood of influencer-driven behavior, whereas higher digital health literacy reduces this likelihood, suggesting a protective effect. Additionally, perceived commercial intent decreases the probability that influencer recommendations lead to action.By distinguishing between engagement and behavioral change, this study reframes influencer effects as conditional outcomes shaped by motivations, perceptions, and interpretive competencies. It contributes to health communication literature by moving beyond linear persuasion models and highlighting the critical role of digital health literacy. The findings also offer practical implications for strengthening individuals' ability to critically evaluate health information in digital environments.Öğe Is Spirulina safe in terms of heavy metals? A public health risk assessment(Springer Nature, 2026) Yaşar, Rüya Kuru; Aytekin, Özlem Üstün; Yılmaz, Şahin; Şahin, FikrettinSpirulina is a microalga/cyanobacterium widely consumed as a dietary supplement due to its high nutrient content and health benefits. While Spirulina is recognized for its contribution to daily mineral intake (e.g., iron, manganese, magnesium, and potassium), its ability to bind heavy metals raises safety concerns, particularly for vulnerable age groups. This study analyzed eight commercial Spirulina supplements (powder and tablet forms) consumed in Türkiye for heavy metal and macro-mineral content using Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). The health risks were assessed across various age groups, including pregnant and breastfeeding women. Significant variability was found in heavy metal and mineral concentrations among the supplements, with one sample (S3) exceeding acceptable Hazard Index (HI) levels for all age groups except adults. Notably, Spirulina supplements generally did not exceed the established dietary reference values or Codex limits for heavy metals, except in certain younger age groups where potential non-carcinogenic risks were observed. The results emphasize the importance of determining safe consumption levels for Spirulina and other algae-based supplements to mitigate risks while maximizing their nutritional benefits. Additionally, the findings highlight the need for public health guidelines to standardize Spirulina’s daily intake and labeling practices.Öğe The relationship between health literacy, nutrition literacy, and beliefs and behaviors related to cancer prevention(2026) Baş, Dilşat; Schoinas, Ezgi Sakar; Kestane, Vahibe UluçayPurpose The study evaluates the relationship between cancer prevention beliefs and health and nutrition literacy, and their impact on healthy eating practices. Methods A cross-sectional study was conducted with 811 voluntary adult participants aged 18 to 65. Data were collected via a five-section questionnaire assessing sociodemographic characteristics, cancer prevention beliefs, Mediterranean Diet Adherence Scale (MEDAS), Turkish Health Literacy Scale-32 (TSOY-32), and Self-Perceived Food Literacy Scale (SPFL). Correlations between participants’ mean scores across the scales were analyzed. Results The mean age of participants was 27.02 ± 10.14 years. Mean scores were 32.01 ± 10.86 for health literacy, 4.00 ± 1.71 for MEDAS, and 89.94 ± 15.46 for SPFL. Fatalistic beliefs about cancer prevention were held by 71.3% of participants. Adequate health literacy and high adherence to the Mediterranean diet were independent variables that increased fatalistic cancer prevention beliefs (p < 0.05), while being over 30 reduced them. Higher education level, perception of health status, adequate nutrition knowledge, and receiving nutrition information from healthcare professionals or dietitians increased health literacy (p < 0.05). Being married, following a special diet, and higher perceived food literacy increased adherence to the Mediterranean diet (p < 0.05). Female gender, regular exercise, and higher perception of health status increased perceived food literacy (p < 0.05). Conclusion Improving health literacy, education level, perception of health status, and nutrition knowledge, along with ensuring health information from professionals such as dietitians, is essential for enhancing fatalistic beliefs about cancer prevention.Öğe Dimensional and cross-sectional compatibility of contemporary nickel–titanium files and their corresponding gutta-percha cones: A micro-computed tomography study(Springer International Publishing, 2026) Sarkan, Cem; Haznedaroğlu, FarukThis study aimed to evaluate the dimensional and sectional compatibility between contemporary nickel–titanium (NiTi) root canal instruments and their corresponding gutta-percha (GP) cones with variable tapers, and to assess their compliance with ISO and ADA standards using micro-computed tomography (Micro-CT). Four NiTi file systems (ProTaper Next X2, HyFlex EDM OneFile, Reciproc Blue R25, and WaveOne Gold Primary) were analyzed. Their compatibility with corresponding GP cones was assessed based on diameter and taper measurements at 1 mm intervals (D1 to D16). Measurements were performed using Micro-CT imaging, and data were analyzed using descriptive statistics, independent t-tests, and one-way ANOVA with Bonferroni post hoc tests (p<0.05). Compliance with International Organization for Standardization (ISO) and American Dental Association (ADA) standards was also assessed. The findings reveal significant dimensional discrepancies between files and GP cones, with GP cones generally exhibiting larger diameters. Reciprocating systems (WaveOne Gold and Reciproc Blue R25) demonstrated superior compatibility with GP cones compared to rotary systems (ProTaper Next and HyFlex EDM OneFile). GP cones adhered more closely to ISO and ADA standards than files. Significant mismatches were identified between NiTi instruments and their corresponding GP cones. Reciprocating systems showed better dimensional compatibility than rotary systems. These results highlight the need for careful evaluation of material pairing to ensure optimal clinical performance.Öğe Aesthetic efficacy of resin infiltration on post-orthodontic white spot lesions using different conditioning methods: 24-month randomized control follow-up(Allen Press Inc., 2026) Karaman, Emel; Ünsal, Kübra Alan; Öz, Aslıhan Zeynep; Öz, Abdullah Alper; Ercin, ÖzlemObjectives: To assess color and fluorescence changes in post-orthodontic white spot lesions (WSLs) using different surface conditioning methods from prior to resin infiltration to a 24-month follow-up. Materials and Methods: Thirty patients, each with a minimum of four WSLs with ICDAS (International Caries Detection and Assessment System) II code 1 and 2 after bracket debonding were included. After baseline (T0), the lesions were randomly divided into four groups: regular brushing, 15% HCl (hydrogen chloride) gel, 37% H3PO4(phosphoric acid) gel, and Er:YAG (erbium-doped yttrium aluminium garnet) laser. Icon resin infiltration was applied. In the treatment groups, color and fluorescence were reexamined just after the resin infiltration treatment (T1), and after 6 (T2) and 24 months (T3). Results: There were no significant fluorescence or color changes between the treatment groups for the different time intervals. The control group showed a significantly lower color change from T0 to T2 and T0 to T3 than all the treatment groups whereas, at T2–T3, the control group showed the greatest improvement. Conclusions: Resin infiltration caused greater esthetic improvement and more revival of the lost fluorescence than daily brushing. HCl gel, H3PO4gel, and Er:YAG laser are adequate conditioning methods for resin infiltration of post-orthodontic WSLs with ICDAS II code 1 and 2. (Angle Orthod. 2026;96:311–317.). © 2026, Allen Press Inc. All rights reserved.Öğe A cross-sectional study on the determinants of parents' giving vitamin C to their children engaged in sportive activities(Campus EDUCA SPORTIS S.L., 2026) Kuyucu, Mihalis; Yücel, Ali Serdar; Korkmaz, Murat; Özpinar, Saliha; Öztaş, Dilek; Düz, Serkan; Cihaner, PerihanThe primary objective of this study is to examine the sociodemographic determinants influencing parents' administration of vitamin C to children participating in sports activities. The research was conducted with the participation of 697 parents residing in various districts of Istanbul and having children aged 9–18 years. Data were collected using a questionnaire and analysed using logistic regression, chi-square test, t-test, and multiple regression analyses in the SPSS 25 programme. The child's regular vitamin C use was considered the dependent variable. The parents' educational level, income level, occupational status, and family structure were evaluated as independent variables. When evaluating the findings, we observed that as the level of education increased, parental awareness became more pronounced. In particular, we found that the rate of regular vitamin C use was significantly higher among children of parents with high income levels, university degrees, and office jobs (p<0.05). Another finding wasthat individuals who exercised regularly were more aware. It was also determined that vitamin C use is more prevalent among children who engage in significantly more weekly exercise and are younger in age (p<0.001). In conclusion, parents' socioeconomic and educational levels play a decisive role in children's immune support behaviours. These findings have the potential to contribute to the development of parent-focused educational programmes and health policies aimed at supporting children's health.
