Exploring Medium- and Long-Term Respiratory and Functional Sequelae in Young Adults Post-COVID-19

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dc.contributor.authorEkşi, Büşra Ülker
dc.contributor.authorKısa, Eylül Pınar
dc.contributor.authorHarputlu, Özge Ertan
dc.contributor.authorKara Kaya, Begüm
dc.contributor.authorHoşbay, Zeynep
dc.contributor.authorAkıncı, Buket
dc.date.accessioned2025-02-03T07:22:26Z
dc.date.available2025-02-03T07:22:26Z
dc.date.issued2025
dc.departmentMeslek Yüksekokulları, Meslek Yüksekokulu, Fizyoterapi Programı
dc.description.abstractBackground and Objectives: Long COVID-19 syndrome may cause difficulties in functionality during daily life in young people. Our objective was to investigate the respiratory and functional sequelae in young adults with asymptomatic or mild COVID-19 compared with healthy peers 3-6 months and 6-12 months after COVID-19 infection. Materials and Methods: Participants aged 18-25 who had COVID-19 within the last 3-6 months (Post-COVID Group 1, n = 25) and 6-12 months (Post-COVID Group 2, n = 25) and age-gender-matched healthy controls (n = 25) were included in this study. Respiratory functions and muscle strength were measured. Physical function was assessed with 6 min walking test (6MWT) and an Incremental Shuttle Walk Test (ISWT). The 1 min sit-to-stand test (1-MSTST) and hand grip strength (HGS) were used to assess muscle performance. Fatigue and dyspnea severity were questioned. Results: The FVC%pred (p = 0.023) and MEP (p = 0.034) were higher, and 1-MSTST repetitions were lower in Post-COVID Group-1 compared to Post-COVID Group-2 (p = 0.029). The PEF%pred (p = 0.025), MEP (p = 0.001), and ISWT distance were lower in Post-COVID Group-2 compared to healthy controls. The number of 1-MSTST repetitions and 6MWT distance were lower in Post-COVID Group-1 (p = 0.003, p = 0.001) and Post-COVID Group-2 (p = 0.003, p = 0.017) than in healthy controls. Exercise-induced blood lactate change during the ISWT, HGS, fatigue, and dyspnea were not significantly different between post-COVID groups and healthy controls. Conclusions: Young adults who pass asymptomatic or mild SARS-CoV-2 infection exhibit a decline in FVC%pred, PEF%pred, lower extremity muscle performance, and physical function within 3-6 months. In addition, the deterioration in respiratory and physical functions becomes apparent within 6-12 months.
dc.identifier.citationÜlker Ekşi, B., Kısa, E. P., Ertan Harputlu, Ö., Kara Kaya, B., Hoşbay, Z., & Akıncı, B. (2025). Exploring Medium- and Long-Term Respiratory and Functional Sequelae in Young Adults Post-COVID-19. Medicina (Kaunas, Lithuania), 61(1), 86. https://doi.org/10.3390/medicina61010086
dc.identifier.doi10.3390/medicina61010086
dc.identifier.endpage99
dc.identifier.issn1010-660X
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85215769064
dc.identifier.scopusqualityQ2
dc.identifier.startpage86
dc.identifier.urihttps://hdl.handle.net/20.500.12941/280
dc.identifier.volume61
dc.identifier.wos001404412900001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.institutionauthorEkşi, Büşra Ülker
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofMedicina (Kaunas, Lithuania)
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectlong COVID-19
dc.subjectphysical function
dc.subjectpost-COVID
dc.subjectrespiratory function
dc.titleExploring Medium- and Long-Term Respiratory and Functional Sequelae in Young Adults Post-COVID-19
dc.typeArticle

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