Predictive values and relationships of serum PSA levels, delta neutrophil index, neutrophil-lymphocyte ratio and other hematological parameters in patients with acute prostatitis

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dc.authoridRamazan Gözüküçük / 0000-0002-8205-4752
dc.contributor.authorUyanık, Bekir Sami
dc.contributor.authorÇakıroğlu, Basri
dc.contributor.authorGözüküçük, Ramazan
dc.date.accessioned2024-09-16T07:19:17Z
dc.date.available2024-09-16T07:19:17Z
dc.date.issued2024
dc.departmentFakülteler, Diş Hekimliği Fakültesi, Temel Bilimler Bölümü
dc.description.abstractBackground: This study aimed to evaluate the predictive values and relationships of serum prostate-specific antigen (PSA) levels, delta neutrophil index (DNI), neutrophil-lymphocyte ratio (NLR), and other hematological parameters in patients diagnosed with acute prostatitis. Methods: Serum PSA levels and hemogram parameters of patients diagnosed with acute prostatitis were retrospectively analyzed. Healthy patients of the same age group were assigned to the control group. WBC, neutrophil, lymphocyte, thrombocyte (PLT), mean platelet volume (MPV), plateletcrit (PCT), NLR, and DNI were determined. Serum total PSA and C-reactive protein (CRP) levels were also assessed. Results: Total PSA levels (3.48 [1.11-6.66]) in the acute prostatitis (AP) group were significantly higher than those of healthy men (0.82 [0.47-1.39]) (p < 0.001). Total CRP levels (3.88 [1.50-22.03]) in the AP group were significantly higher than those in healthy men (1.15 [0.89-2.00]) (p < 0.001). The sensitivity and specificity of PSA at a cutoff value of 1.52 were 68.4% and 79.7%, respectively. The NLR value in the AP group was 2.62 (1.87-4.42), compared to 1.63 (1.18-2.20) in the healthy group (p < 0.001). Differences in WBC, neutrophil, and lymphocyte counts were also statistically significant (p < 0.001). There were no significant differences in PLT, PCT, or DNI values. Significant positive correlations were observed between PSA, CRP, and DNI values (all p < 0.001). Conclusion: This study demonstrated the usefulness of NLR, PSA, CRP, and WBC as predictors of acute prostatitis. NLR is a simple, inexpensive inflammation parameter that correlates well with CRP levels.
dc.identifier.citationUyanık, B. S., Cakiroglu, B., & Gozukucuk, R. (2024). Predictive values and relationships of serum PSA levels, delta neutrophil index, neutrophil-lymphocyte ratio and other hematological parameters in patients with acute prostatitis. Urologia, 3915603241273883. Advance online publication. https://doi.org/10.1177/03915603241273883en_US
dc.identifier.scopus2-s2.0-85203021128
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://hdl.handle.net/20.500.12941/257
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGözüküçük, Ramazan
dc.language.isoen
dc.publisherUrologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectSevimli prostatit
dc.subjectCute prostatitis
dc.subjectDelta nötrofil indeksi
dc.subjectDelta neutrophil index
dc.subjectNötrofil-lenfosit oranı
dc.subjectNeutrophil-lymphocyte ratio
dc.subjectProstat spesifik antijen
dc.subjectProstate-specific antigen
dc.titlePredictive values and relationships of serum PSA levels, delta neutrophil index, neutrophil-lymphocyte ratio and other hematological parameters in patients with acute prostatitis
dc.typeArticle

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