Efficacy of the Mediterranean Diet Containing Different Macronutrients on Non-Alcoholic Fatty Liver Disease

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Tarih

2024

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Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

This study aimed to investigate the effects of the typical Mediterranean diet (TMD), low-carbohydrate Mediterranean diet (LCMD), and low-fat Mediterranean diet (LFMD) on biochemical findings, fatty liver index (FLI), anthropometric measurements, and body composition in individuals with obesity with non-alcoholic fatty liver disease (NAFLD) and insulin resistance. This study included 63 participants with obesity with insulin resistance diagnosed with NAFLD by ultrasonography to investigate the effects of an 8-week energy-restricted TMD, LCMD, and LFMD on biochemical findings, FLI, fibrosis-4 index (FIB-4), anthropometric measurements, and body composition. Patients were randomized into three groups and were interviewed face-to-face every week. According to the food consumption records (baseline end), the difference in the amount of sucrose and total fat consumed in the TMD group; the difference in energy intake from sucrose, monounsaturated fatty acids, and oleic acid in the LCMD group; and the difference in energy intake from fiber, sucrose, monounsaturated and polyunsaturated fatty acids, and cholesterol in the LFMD group showed significant correlations with liver enzymes and FLI (p < 0.05). In conclusion, although it has a different macronutrient composition, the Mediterranean diet may positively affect biochemical parameters and FLI in individuals with NAFLD, albeit in different ways.

Açıklama

Anahtar Kelimeler

Yağlı karaciğer indeksi, Fatty liver index, Karaciğer enzimleri, Liver enzymes, Akdeniz diyeti, Mediterranean diet, Alkolsüz yağlı karaciğer hastalığı, Non-alcoholic fatty liver disease, Steatohepatit, Steatohepatitis

Kaynak

Nutrients

WoS Q Değeri

Scopus Q Değeri

Q1

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Künye

Uluçay Kestane, V., & Baş, M. (2024). Efficacy of the Mediterranean Diet Containing Different Macronutrients on Non-Alcoholic Fatty Liver Disease. Nutrients, 16(16), 2699. https://doi.org/10.3390/nu16162699