Efficacy of the Mediterranean Diet Containing Different Macronutrients on Non-Alcoholic Fatty Liver Disease

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dc.authoridVahibe Uluçay Kestane / 0009-0008-2088-0566
dc.contributor.authorUluçay Kestane, Vahibe
dc.contributor.authorBaş, Murat
dc.date.accessioned2024-09-06T09:48:22Z
dc.date.available2024-09-06T09:48:22Z
dc.date.issued2024
dc.departmentFakülteler, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü
dc.description.abstractThis study aimed to investigate the effects of the typical Mediterranean diet (TMD), low-carbohydrate Mediterranean diet (LCMD), and low-fat Mediterranean diet (LFMD) on biochemical findings, fatty liver index (FLI), anthropometric measurements, and body composition in individuals with obesity with non-alcoholic fatty liver disease (NAFLD) and insulin resistance. This study included 63 participants with obesity with insulin resistance diagnosed with NAFLD by ultrasonography to investigate the effects of an 8-week energy-restricted TMD, LCMD, and LFMD on biochemical findings, FLI, fibrosis-4 index (FIB-4), anthropometric measurements, and body composition. Patients were randomized into three groups and were interviewed face-to-face every week. According to the food consumption records (baseline end), the difference in the amount of sucrose and total fat consumed in the TMD group; the difference in energy intake from sucrose, monounsaturated fatty acids, and oleic acid in the LCMD group; and the difference in energy intake from fiber, sucrose, monounsaturated and polyunsaturated fatty acids, and cholesterol in the LFMD group showed significant correlations with liver enzymes and FLI (p < 0.05). In conclusion, although it has a different macronutrient composition, the Mediterranean diet may positively affect biochemical parameters and FLI in individuals with NAFLD, albeit in different ways.
dc.identifier.citationUluçay Kestane, V., & Baş, M. (2024). Efficacy of the Mediterranean Diet Containing Different Macronutrients on Non-Alcoholic Fatty Liver Disease. Nutrients, 16(16), 2699. https://doi.org/10.3390/nu16162699en_US
dc.identifier.doi10.3390/nu16162699
dc.identifier.endpage17
dc.identifier.issn2072-6643
dc.identifier.scopus2-s2.0-85202592382
dc.identifier.scopusqualityQ1
dc.identifier.startpage2
dc.identifier.urihttps://hdl.handle.net/20.500.12941/254
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorUluçay Kestane, Vahibe
dc.language.isoen
dc.relation.ispartofNutrients
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectYağlı karaciğer indeksi
dc.subjectFatty liver index
dc.subjectKaraciğer enzimleri
dc.subjectLiver enzymes
dc.subjectAkdeniz diyeti
dc.subjectMediterranean diet
dc.subjectAlkolsüz yağlı karaciğer hastalığı
dc.subjectNon-alcoholic fatty liver disease
dc.subjectSteatohepatit
dc.subjectSteatohepatitis
dc.titleEfficacy of the Mediterranean Diet Containing Different Macronutrients on Non-Alcoholic Fatty Liver Disease
dc.typeArticle

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